このたび、“Hierarchical clustering of therapeutic proteins based on agitation-induced aggregation propensity and its relation to physicochemical parameters“と題する最新の研究論文がアクセプトされましたのでご紹介いたします。

本研究では、物理的ストレスによる治療用タンパク質の凝集を抑制するため、異なる製剤条件下での安定性を評価し、凝集傾向に応じた分類と最適な製剤戦略を提案しています。

本論文の詳細は、こちらのリンクよりご覧いただけます。

We are pleased to announce that our latest research paper entitled “Hierarchical clustering of therapeutic proteins based on agitation-induced aggregation propensity and its relation to Hierarchical clustering of therapeutic proteins based on agitation-induced aggregation propensity and its relation to physicochemical parameters” has been accepted for publication.

In this study, we evaluate the stability of therapeutic proteins under different formulation conditions and propose a classification and optimal formulation strategy based on aggregation propensity in order to suppress aggregation of therapeutic proteins due to physical stress.

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